Major League Baseball » St. Louis Cardinals » Biggest Losses
Based on run differential, the largest loss in St. Louis Cardinals history is by 23 runs, which occured in a 2-25 loss to the Pittsburgh Pirates on Aug 1, 1893.
The largest shutout loss in St. Louis Cardinals history is 19-0, which happened in a loss to the Pittsburgh Pirates on Aug 3, 1961.
The biggest postseason loss in St. Louis Cardinals history, by run differential, is by 15 runs which occured in a 0-15 loss to the Atlanta Braves during the NL Championship Series on Oct 17, 1996.
The biggest home loss in St. Louis Cardinals history, by run differential, is by 23 runs which occured in a 2-25 loss to the Pittsburgh Pirates on Aug 1, 1893.
The biggest road loss in St. Louis Cardinals history, by run differential, is by 21 runs, which has happened 3 times.
The most runs the St. Louis Cardinals have ever allowed in a single game is 28 runs, which they gave up in a 7-28 loss to the Boston Beaneaters on Sep 3, 1896.
| Opponent | Run Margin | Date | Score |
|---|---|---|---|
| Arizona Diamondbacks | 13 (2x) (2 times) |
Apr 23, 2024
Apr 17, 2001 |
1-14
4-17 |
| Atlanta Braves | 21 | Sep 3, 1896 | 7-28 |
| Baltimore Orioles | 10 | Aug 8, 2014 | 2-12 |
| Boston Red Sox | 12 | Jun 11, 2003 | 1-13 |
| Chicago Cubs | 18 | Aug 1, 1894 | 8-26 |
| Chicago White Sox | 14 | Jun 20, 2006 | 6-20 |
| Cincinnati Reds | 17 | Sep 29, 2023 | 2-19 |
| Cleveland Guardians | 12 (2x) (2 times) |
Aug 28, 2020
Jul 6, 2001 |
2-14
2-14 |
| Colorado Rockies | 11 (3x) (3 times) |
Aug 9, 2022
Jul 16, 1994 May 28, 2011 |
5-16
4-15 4-15 |
| Detroit Tigers | 10 | May 18, 2007 | 4-14 |
| Houston Astros | 17 | Sep 20, 2007 | 1-18 |
| Kansas City Royals | 11 | Aug 30, 1997 | 5-16 |
| Los Angeles Angels | 6 | Jun 9, 2007 | 3-9 |
| Los Angeles Dodgers | 16 (2x) (2 times) |
Aug 30, 1953
Aug 20, 1894 |
4-20
4-20 |
| Miami Marlins | 13 | Jul 4, 2023 | 2-15 |
| Milwaukee Brewers | 15 | Sep 15, 2020 | 3-18 |
| Minnesota Twins | 7 | Jul 31, 2021 | 1-8 |
| New York Mets | 13 (2x) (2 times) |
Sep 24, 1988
Jul 1, 1976 |
1-14
0-13 |
| New York Yankees | 9 | Jun 14, 2003 | 4-13 |
| Oakland Athletics | 11 | Jun 15, 2007 | 3-14 |
| Philadelphia Phillies | 20 | Sep 24, 1894 | 1-21 |
| Pittsburgh Pirates | 23 | Aug 1, 1893 | 2-25 |
| San Diego Padres | 13 | Aug 24, 1993 | 4-17 |
| San Francisco Giants | 19 | Jul 9, 1988 | 2-21 |
| Seattle Mariners | 10 | Jun 10, 2002 | 0-10 |
| Tampa Bay Rays | 8 | Jun 8, 2022 | 3-11 |
| Texas Rangers | 5 | Jun 12, 2004 | 2-7 |
| Toronto Blue Jays | 7 (2x) (2 times) |
Jul 26, 2022
May 24, 2022 |
3-10
1-8 |
| Washington Nationals | 16 | Jun 8, 1990 | 2-18 |
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