National Football League » New England Patriots » Biggest Wins
Based on point differential, the largest win in New England Patriots history is by 59 points, which occured in a 59-0 win over the Tennessee Titans on Oct 18, 2009.
The biggest playoffs win in New England Patriots history, by point differential, is by 38 points which occured in a 45-7 win over the Indianapolis Colts during the Conference Championship on Jan 18, 2015.
The biggest home win in New England Patriots history, by point differential, is by 59 points which occured in a 59-0 win over the Tennessee Titans during the on Oct 18, 2009.
The biggest road win in New England Patriots history, by point differential, is by 46 points which occured in a 56-10 win over the Buffalo Bills during the on Nov 18, 2007.
The most points the New England Patriots have ever scored in a single game is 59 points, which has happened twice: a 59-0 win against the Tennessee Titans on Oct 18, 2009 and a 59-24 win against the Indianapolis Colts on Nov 18, 2012.
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