Major League Baseball » Arizona Diamondbacks » Biggest Losses
Based on run differential, the largest loss in Arizona Diamondbacks history is by 21 runs, which occured in a 1-22 loss to the Los Angeles Dodgers on Jul 10, 2021.
| Opponent | Run Margin | Date | Score |
|---|---|---|---|
| Atlanta Braves | 14 | Jul 29, 2007 | 0-14 |
| Baltimore Orioles | 6 (2x) (2 times) |
Jun 9, 2004
Jun 22, 2007 |
2-8
1-7 |
| Boston Red Sox | 14 | Aug 14, 2016 | 2-16 |
| Chicago Cubs | 12 | Aug 1, 2017 | 4-16 |
| Chicago White Sox | 6 (3x) (3 times) |
May 9, 2014
Jun 19, 2011 Jun 15, 2005 |
3-9
2-8 6-12 |
| Cincinnati Reds | 14 | Aug 19, 2005 | 3-17 |
| Cleveland Guardians | 9 | Jun 18, 2023 | 3-12 |
| Colorado Rockies | 17 (2x) (2 times) |
Jul 11, 2018
Jun 18, 2000 |
2-19
2-19 |
| Detroit Tigers | 6 (2x) (2 times) |
Jul 23, 2014
Jun 25, 2011 |
5-11
0-6 |
| Houston Astros | 16 | Oct 2, 2015 | 5-21 |
| Kansas City Royals | 10 | Aug 5, 2014 | 2-12 |
| Los Angeles Angels | 9 | Jun 26, 2009 | 3-12 |
| Los Angeles Dodgers | 21 | Jul 10, 2021 | 1-22 |
| Miami Marlins | 9 (4x) (4 times) |
Aug 20, 2012
Aug 14, 2007 May 22, 2004 Sep 2, 2000 |
3-12
5-14 2-11 1-10 |
| Milwaukee Brewers | 14 | May 8, 2010 | 3-17 |
| Minnesota Twins | 11 | Aug 5, 2023 | 1-12 |
| New York Mets | 14 | Aug 24, 2005 | 4-18 |
| New York Yankees | 6 (3x) (3 times) |
Jun 14, 2007
Jun 22, 2010 Sep 22, 2023 |
1-7
3-9 1-7 |
| Oakland Athletics | 14 | Jun 17, 2008 | 1-15 |
| Philadelphia Phillies | 16 | Aug 31, 2022 | 2-18 |
| Pittsburgh Pirates | 14 | May 8, 2005 | 2-16 |
| San Diego Padres | 12 (3x) (3 times) |
May 4, 2024
Sep 3, 2003 Jul 10, 2003 |
1-13
0-12 2-14 |
| San Francisco Giants | 13 (2x) (2 times) |
Jul 12, 2022
Jul 1, 2007 |
0-13
0-13 |
| Seattle Mariners | 8 | Jul 15, 2001 | 0-8 |
| St. Louis Cardinals | 12 | Sep 23, 2002 | 1-13 |
| Tampa Bay Rays | 11 | May 6, 2019 | 1-12 |
| Texas Rangers | 11 | Jun 23, 1998 | 5-16 |
| Toronto Blue Jays | 11 | Jun 12, 2004 | 4-15 |
| Washington Nationals | 15 | May 14, 2021 | 2-17 |
| Opponent | Run Margin | Date | Score |
|---|---|---|---|
| Atlanta Braves | 7 | Oct 17, 2001 | 1-8 |
| Baltimore Orioles | – | – | – |
| Boston Red Sox | – | – | – |
| Chicago Cubs | – | – | – |
| Chicago White Sox | – | – | – |
| Cincinnati Reds | – | – | – |
| Cleveland Guardians | – | – | – |
| Colorado Rockies | 4 | Oct 11, 2007 | 1-5 |
| Detroit Tigers | – | – | – |
| Houston Astros | – | – | – |
| Kansas City Royals | – | – | – |
| Los Angeles Angels | – | – | – |
| Los Angeles Dodgers | 4 | Oct 6, 2017 | 5-9 |
| Miami Marlins | – | – | – |
| Milwaukee Brewers | 5 | Oct 2, 2011 | 4-9 |
| Minnesota Twins | – | – | – |
| New York Mets | 7 | Oct 8, 1999 | 2-9 |
| New York Yankees | 1 (3x) (3 times) |
Nov 1, 2001
Oct 31, 2001 Oct 30, 2001 |
2-3
3-4 1-2 |
| Oakland Athletics | – | – | – |
| Philadelphia Phillies | 10 | Oct 17, 2023 | 0-10 |
| Pittsburgh Pirates | – | – | – |
| San Diego Padres | – | – | – |
| San Francisco Giants | – | – | – |
| Seattle Mariners | – | – | – |
| St. Louis Cardinals | 10 | Oct 1, 2002 | 2-12 |
| Tampa Bay Rays | – | – | – |
| Texas Rangers | 5 | Nov 1, 2023 | 0-5 |
| Toronto Blue Jays | – | – | – |
| Washington Nationals | – | – | – |
The largest shutout loss in Arizona Diamondbacks history is 14-0, which happened in a loss to the Atlanta Braves on Jul 29, 2007.
The biggest postseason loss in Arizona Diamondbacks history, by run differential, is by 10 runs, which has happened twice: a 0-10 loss to the Philadelphia Phillies on Oct 17, 2023 and a 2-12 loss to the St. Louis Cardinals on Oct 1, 2002.
The biggest home loss in Arizona Diamondbacks history, by run differential, is by 18 runs which occured in a 1-19 loss to the Los Angeles Dodgers during the on Sep 2, 2002.
The biggest road loss in Arizona Diamondbacks history, by run differential, is by 21 runs which occured in a 1-22 loss to the Los Angeles Dodgers on Jul 10, 2021.
The most runs the Arizona Diamondbacks have ever allowed in a single game is 22 runs, which they gave up in a 1-22 loss to the Los Angeles Dodgers on Jul 10, 2021.
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