| 6-10 | Missed Playoffs |
| Record | Outcome |
The San Francisco 49ers finished the regular season with a 6-10 record. They went 4-4 at home and 2-6 on the road.
The 1980 San Francisco 49ers played in the West Division of the National Football Conference.
During the regular season, the 1980 San Francisco 49ers went 2-4 against their NFC West opponents.
No, the 49ers didn't make the Playoffs in 1980.
The San Francisco 49ers finished the regular season with a point differential of -95. Based on their point differential and their pythagorean expectation, the 49ers could have been expected to have about 5.6 wins, or a 6-10 record in the regular season.
In close, one-score games, the 1980 San Francisco 49ers went 4-6. In games decided by a field goal or less, the 49ers went 3-2.
During the regular season, the 1980 San Francisco 49ers went 2-0 in overtime games.
The longest win streak during the regular season for the 1980 San Francisco 49ers was a 3 game winning streak on 2 separate stretches during the season.
The longest losing streak that the San Francisco 49ers had during the 1980 regular season was 8 games, which happened once during the season.
= Playoff Team
= Division Opponent
| Week | Date | Opponent | Score | |
|---|---|---|---|---|
| Regular Season | ||||
| 1 | Sun, Sep 7, 1980 Sun, Sep 7 | @ New Orleans Saints Saints | Win W 26 - 23 | |
| 2 | Sun, Sep 14, 1980 Sun, Sep 14 | vs St. Louis Cardinals Cardinals | Win W 24 - 21 | OT |
| 3 | Sun, Sep 21, 1980 Sun, Sep 21 | @ New York Jets Jets | Win W 37 - 27 | |
| 4 | Sun, Sep 28, 1980 Sun, Sep 28 | vs Atlanta Falcons Falcons | Loss L 17 - 20 | |
| 5 | Sun, Oct 5, 1980 Sun, Oct 5 | @ Los Angeles Rams Rams | Loss L 26 - 48 | |
| 6 | Sun, Oct 12, 1980 Sun, Oct 12 | @ Dallas Cowboys Cowboys | Loss L 14 - 59 | |
| 7 | Sun, Oct 19, 1980 Sun, Oct 19 | vs Los Angeles Rams Rams | Loss L 17 - 31 | |
| 8 | Sun, Oct 26, 1980 Sun, Oct 26 | vs Tampa Bay Buccaneers Buccaneers | Loss L 23 - 24 | |
| 9 | Sun, Nov 2, 1980 Sun, Nov 2 | @ Detroit Lions Lions | Loss L 13 - 17 | |
| 10 | Sun, Nov 9, 1980 Sun, Nov 9 | @ Green Bay Packers Packers | Loss L 16 - 23 | |
| 11 | Sun, Nov 16, 1980 Sun, Nov 16 | @ Miami Dolphins Dolphins | Loss L 13 - 17 | |
| 12 | Sun, Nov 23, 1980 Sun, Nov 23 | vs New York Giants Giants | Win W 12 - 0 | |
| 13 | Sun, Nov 30, 1980 Sun, Nov 30 | vs New England Patriots Patriots | Win W 21 - 17 | |
| 14 | Sun, Dec 7, 1980 Sun, Dec 7 | vs New Orleans Saints Saints | Win W 38 - 35 | OT |
| 15 | Sun, Dec 14, 1980 Sun, Dec 14 | @ Atlanta Falcons Falcons | Loss L 10 - 35 | |
| 16 | Sun, Dec 21, 1980 Sun, Dec 21 | vs Buffalo Bills Bills | Loss L 13 - 18 | |
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