| 6-10 | Missed Playoffs |
| Record | Outcome |
The San Francisco 49ers finished the regular season with a 6-10 record. They went 4-4 at home and 2-6 on the road.
The 2000 San Francisco 49ers played in the West Division of the National Football Conference.
During the regular season, the 2000 San Francisco 49ers went 1-7 against their NFC West opponents.
No, the 49ers didn't make the Playoffs in 2000.
The San Francisco 49ers finished the regular season with a point differential of -34. Based on their point differential and their pythagorean expectation, the 49ers could have been expected to have about 7.2 wins, or a 7-9 record in the regular season.
In close, one-score games, the 2000 San Francisco 49ers went 1-4. In games decided by a field goal or less, the 49ers went 0-2.
During the regular season, the 2000 San Francisco 49ers went 0-1 in overtime games.
The longest win streak during the regular season for the 2000 San Francisco 49ers was a 3 game winning streak.
The longest losing streak that the San Francisco 49ers had during the 2000 regular season was 5 games, which happened once during the season.
= Playoff Team
= Division Opponent
| Week | Date | Opponent | Score | |
|---|---|---|---|---|
| Regular Season | ||||
| 1 | Sun, Sep 3, 2000 Sun, Sep 3 | @ Atlanta Falcons Falcons | Loss L 28 - 36 | |
| 2 | Sun, Sep 10, 2000 Sun, Sep 10 | vs Carolina Panthers Panthers | Loss L 22 - 38 | |
| 3 | Sun, Sep 17, 2000 Sun, Sep 17 | @ St. Louis Rams Rams | Loss L 24 - 41 | |
| 4 | Sun, Sep 24, 2000 Sun, Sep 24 | @ Dallas Cowboys Cowboys | Win W 41 - 24 | |
| 5 | Sun, Oct 1, 2000 Sun, Oct 1 | vs Arizona Cardinals Cardinals | Win W 27 - 20 | |
| 6 | Sun, Oct 8, 2000 Sun, Oct 8 | vs Oakland Raiders Raiders | Loss L 28 - 34 | OT |
| 7 | Sun, Oct 15, 2000 Sun, Oct 15 | @ Green Bay Packers Packers | Loss L 28 - 31 | |
| 8 | Sun, Oct 22, 2000 Sun, Oct 22 | @ Carolina Panthers Panthers | Loss L 16 - 34 | |
| 9 | Sun, Oct 29, 2000 Sun, Oct 29 | vs St. Louis Rams Rams | Loss L 24 - 34 | |
| 10 | Sun, Nov 5, 2000 Sun, Nov 5 | @ New Orleans Saints Saints | Loss L 15 - 31 | |
| 11 | Sun, Nov 12, 2000 Sun, Nov 12 | vs Kansas City Chiefs Chiefs | Win W 21 - 7 | |
| 12 | Sun, Nov 19, 2000 Sun, Nov 19 | vs Atlanta Falcons Falcons | Win W 16 - 6 | |
| 14 | Sun, Dec 3, 2000 Sun, Dec 3 | @ San Diego Chargers Chargers | Win W 45 - 17 | |
| 15 | Sun, Dec 10, 2000 Sun, Dec 10 | vs New Orleans Saints Saints | Loss L 27 - 31 | |
| 16 | Sun, Dec 17, 2000 Sun, Dec 17 | vs Chicago Bears Bears | Win W 17 - 0 | |
| 17 | Sat, Dec 23, 2000 Sat, Dec 23 | @ Denver Broncos Broncos | Loss L 9 - 38 | |
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