| 12-4 | Lost Wild Card |
| Record | Outcome |
The San Francisco 49ers finished the regular season with a 12-4 record. They went 7-1 at home and 5-3 on the road. Including the playoffs, the San Francisco 49ers went 12-5. Their final game was a loss in the Wild Card Round to the Green Bay Packers.
Yes, the San Francisco 49ers made the Playoffs in 2001. They lost their only game against the Green Bay Packers in the Wild Card Round.
The San Francisco 49ers finished the regular season with a point differential of +127. Based on their point differential and their pythagorean expectation, the 49ers could have been expected to have about 11.3 wins.
In close, one-score games, the 2001 San Francisco 49ers went 6-3. In games decided by a field goal or less, the 49ers went 5-1.
During the regular season, the 2001 San Francisco 49ers went 3-1 in overtime games.
| Week | Date | Opponent | Score | |
|---|---|---|---|---|
| 1 | Sun, Sep 9, 2001 Sun, Sep 9 | vs Atlanta Falcons Falcons | Win W 16 - 13 | OT |
| 2 | Sun, Sep 23, 2001 Sun, Sep 23 | vs St. Louis Rams Rams | Loss L 26 - 30 | |
| 3 | Mon, Oct 1, 2001 Mon, Oct 1 | @ New York Jets Jets | Win W 19 - 17 | |
| 4 | Sun, Oct 7, 2001 Sun, Oct 7 | vs Carolina Panthers Panthers | Win W 24 - 14 | |
| 5 | Sun, Oct 14, 2001 Sun, Oct 14 | @ Atlanta Falcons Falcons | Win W 37 - 31 | OT |
| 7 | Sun, Oct 28, 2001 Sun, Oct 28 | @ Chicago Bears Bears | Loss L 31 - 37 | OT |
| 8 | Sun, Nov 4, 2001 Sun, Nov 4 | vs Detroit Lions Lions | Win W 21 - 13 | |
| 9 | Sun, Nov 11, 2001 Sun, Nov 11 | vs New Orleans Saints Saints | Win W 28 - 27 | |
| 10 | Sun, Nov 18, 2001 Sun, Nov 18 | @ Carolina Panthers Panthers | Win W 25 - 22 | OT |
| 11 | Sun, Nov 25, 2001 Sun, Nov 25 | @ Indianapolis Colts Colts | Win W 40 - 21 | |
| 12 | Sun, Dec 2, 2001 Sun, Dec 2 | vs Buffalo Bills Bills | Win W 35 - 0 | |
| 13 | Sun, Dec 9, 2001 Sun, Dec 9 | @ St. Louis Rams Rams | Loss L 14 - 27 | |
| 14 | Sun, Dec 16, 2001 Sun, Dec 16 | vs Miami Dolphins Dolphins | Win W 21 - 0 | |
| 15 | Sat, Dec 22, 2001 Sat, Dec 22 | vs Philadelphia Eagles Eagles | Win W 13 - 3 | |
| 16 | Sun, Dec 30, 2001 Sun, Dec 30 | @ Dallas Cowboys Cowboys | Loss L 21 - 27 | |
| 17 | Sun, Jan 6, 2002 Sun, Jan 6, 2002 | @ New Orleans Saints Saints | Win W 38 - 0 | |
| Playoffs | ||||
| Wild Card Wild Card Round | Sun, Jan 13, 2002 Sun, Jan 13, 2002 | @ Green Bay Packers Packers | Loss L 15 - 25 | |
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