| 6-10 | Missed Playoffs |
| Record | Outcome |
The St. Louis Rams finished the regular season with a 6-10 record. They went 3-5 at home and 3-5 on the road.
No, the Rams didn't make the Playoffs in 2005.
The St. Louis Rams finished the regular season with a point differential of -66. Based on their point differential and their pythagorean expectation, the Rams could have been expected to have about 6.4 wins.
In close, one-score games, the 2005 St. Louis Rams went 4-4. In games decided by a field goal or less, the Rams went 2-2.
During the regular season, the 2005 St. Louis Rams went 1-0 in overtime games.
| Week | Date | Opponent | Score | |
|---|---|---|---|---|
| 1 | Sun, Sep 11, 2005 Sun, Sep 11 | @ San Francisco 49ers 49ers | Loss L 25 - 28 | |
| 2 | Sun, Sep 18, 2005 Sun, Sep 18 | @ Arizona Cardinals Cardinals | Win W 17 - 12 | |
| 3 | Sun, Sep 25, 2005 Sun, Sep 25 | vs Tennessee Titans Titans | Win W 31 - 27 | |
| 4 | Sun, Oct 2, 2005 Sun, Oct 2 | @ New York Giants Giants | Loss L 24 - 44 | |
| 5 | Sun, Oct 9, 2005 Sun, Oct 9 | vs Seattle Seahawks Seahawks | Loss L 31 - 37 | |
| 6 | Mon, Oct 17, 2005 Mon, Oct 17 | @ Indianapolis Colts Colts | Loss L 28 - 45 | |
| 7 | Sun, Oct 23, 2005 Sun, Oct 23 | vs New Orleans Saints Saints | Win W 28 - 17 | |
| 8 | Sun, Oct 30, 2005 Sun, Oct 30 | vs Jacksonville Jaguars Jaguars | Win W 24 - 21 | |
| 10 | Sun, Nov 13, 2005 Sun, Nov 13 | @ Seattle Seahawks Seahawks | Loss L 16 - 31 | |
| 11 | Sun, Nov 20, 2005 Sun, Nov 20 | vs Arizona Cardinals Cardinals | Loss L 28 - 38 | |
| 12 | Sun, Nov 27, 2005 Sun, Nov 27 | @ Houston Texans Texans | Win W 33 - 27 | OT |
| 13 | Sun, Dec 4, 2005 Sun, Dec 4 | vs Washington Redskins Redskins | Loss L 9 - 24 | |
| 14 | Sun, Dec 11, 2005 Sun, Dec 11 | @ Minnesota Vikings Vikings | Loss L 13 - 27 | |
| 15 | Sun, Dec 18, 2005 Sun, Dec 18 | vs Philadelphia Eagles Eagles | Loss L 16 - 17 | |
| 16 | Sat, Dec 24, 2005 Sat, Dec 24 | vs San Francisco 49ers 49ers | Loss L 20 - 24 | |
| 17 | Sun, Jan 1, 2006 Sun, Jan 1, 2006 | @ Dallas Cowboys Cowboys | Win W 20 - 10 | |
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