| 6-10 | Missed Playoffs |
| Record | Outcome |
The Detroit Lions finished the regular season with a 6-10 record. They went 4-4 at home and 2-6 on the road.
No, the Lions didn't make the Playoffs in 2010.
The Detroit Lions finished the regular season with a point differential of -7. Based on their point differential and their pythagorean expectation, the Lions could have been expected to have about 7.8 wins.
In close, one-score games, the 2010 Detroit Lions went 4-7. In games decided by a field goal or less, the Lions went 1-4.
During the regular season, the 2010 Detroit Lions went 1-1 in overtime games.
| Week | Date | Opponent | Score | |
|---|---|---|---|---|
| 1 | Sun, Sep 12, 2010 Sun, Sep 12 | @ Chicago Bears Bears | Loss L 14 - 19 | |
| 2 | Sun, Sep 19, 2010 Sun, Sep 19 | vs Philadelphia Eagles Eagles | Loss L 32 - 35 | |
| 3 | Sun, Sep 26, 2010 Sun, Sep 26 | @ Minnesota Vikings Vikings | Loss L 10 - 24 | |
| 4 | Sun, Oct 3, 2010 Sun, Oct 3 | @ Green Bay Packers Packers | Loss L 26 - 28 | |
| 5 | Sun, Oct 10, 2010 Sun, Oct 10 | vs St. Louis Rams Rams | Win W 44 - 6 | |
| 6 | Sun, Oct 17, 2010 Sun, Oct 17 | @ New York Giants Giants | Loss L 20 - 28 | |
| 8 | Sun, Oct 31, 2010 Sun, Oct 31 | vs Washington Redskins Redskins | Win W 37 - 25 | |
| 9 | Sun, Nov 7, 2010 Sun, Nov 7 | vs New York Jets Jets | Loss L 20 - 23 | OT |
| 10 | Sun, Nov 14, 2010 Sun, Nov 14 | @ Buffalo Bills Bills | Loss L 12 - 14 | |
| 11 | Sun, Nov 21, 2010 Sun, Nov 21 | @ Dallas Cowboys Cowboys | Loss L 19 - 35 | |
| 12 | Thu, Nov 25, 2010 Thu, Nov 25 | vs New England Patriots Patriots | Loss L 24 - 45 | |
| 13 | Sun, Dec 5, 2010 Sun, Dec 5 | vs Chicago Bears Bears | Loss L 20 - 24 | |
| 14 | Sun, Dec 12, 2010 Sun, Dec 12 | vs Green Bay Packers Packers | Win W 7 - 3 | |
| 15 | Sun, Dec 19, 2010 Sun, Dec 19 | @ Tampa Bay Buccaneers Buccaneers | Win W 23 - 20 | OT |
| 16 | Sun, Dec 26, 2010 Sun, Dec 26 | @ Miami Dolphins Dolphins | Win W 34 - 27 | |
| 17 | Sun, Jan 2, 2011 Sun, Jan 2, 2011 | vs Minnesota Vikings Vikings | Win W 20 - 13 | |
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