The Indianapolis Colts and the Seattle Seahawks tied for the best record in the regular season through week 16 at 13-2.
The Indianapolis Colts had the best point differential in the 2005 regular season through week 16 at +188 points.
The San Francisco 49ers had the worst point differential in the 2005 regular season through week 16 at -192 points.
The Seattle Seahawks had the most points per game in the 2005 regular season through week 16 at 29.0 PPG.
The Chicago Bears allowed the fewest points per game in the 2005 regular season through week 16 at 11.2 points allowed per game.
The games for week 16 of the 2005 NFL regular season were played on Saturday, Dec 24, 2005, Sunday, Dec 25, 2005 and Monday, Dec 26, 2005.
| Team | Record | Streak | PPG | PPG Allowed | Point Differential | Playoff Result |
|---|---|---|---|---|---|---|
| Indianapolis Colts | 13-2 | L2 | 28.1 | 15.6 | +188 | Lost Divisional |
| Seattle Seahawks | 13-2 | W11 | 29.0 | 16.5 | +187 | Lost SB |
| Denver Broncos | 12-3 | W3 | 24.8 | 16.7 | +121 | Lost Conf Champ |
| Cincinnati Bengals | 11-4 | L1 | 27.9 | 20.9 | +105 | Lost Wild Card |
| Chicago Bears | 11-4 | W2 | 16.7 | 11.2 | +82 | Lost Divisional |
| Jacksonville Jaguars | 11-4 | W2 | 21.4 | 17.1 | +65 | Lost Wild Card |
| Pittsburgh Steelers | 10-5 | W3 | 23.6 | 15.8 | +117 | Won SB |
| New York Giants | 10-5 | L1 | 26.1 | 19.5 | +99 | Lost Wild Card |
| Carolina Panthers | 10-5 | L1 | 23.1 | 16.5 | +99 | Lost Conf Champ |
| New England Patriots | 10-5 | W4 | 23.5 | 20.7 | +43 | Lost Divisional |
| Tampa Bay Buccaneers | 10-5 | W1 | 18.2 | 17.4 | +12 | Lost Wild Card |
| San Diego Chargers | 9-6 | L1 | 27.4 | 19.3 | +122 | |
| Washington Redskins | 9-6 | W4 | 21.9 | 18.2 | +55 | Lost Divisional |
| Kansas City Chiefs | 9-6 | W1 | 24.4 | 21.5 | +44 | |
| Dallas Cowboys | 9-6 | W1 | 21.0 | 19.2 | +27 | |
| Atlanta Falcons | 8-7 | L2 | 22.7 | 19.8 | +43 | |
| Miami Dolphins | 8-7 | W5 | 19.3 | 19.4 | -1 | |
| Minnesota Vikings | 8-7 | L2 | 18.1 | 22.3 | -62 | |
| Baltimore Ravens | 6-9 | W2 | 16.6 | 18.6 | -30 | |
| Philadelphia Eagles | 6-9 | L1 | 19.3 | 23.8 | -67 | |
| Arizona Cardinals | 5-10 | W1 | 19.9 | 24.7 | -72 | |
| Cleveland Browns | 5-10 | L1 | 14.1 | 19.0 | -73 | |
| St. Louis Rams | 5-10 | L4 | 22.9 | 27.9 | -76 | |
| Detroit Lions | 5-10 | W1 | 15.5 | 20.7 | -77 | |
| Buffalo Bills | 5-10 | W1 | 16.3 | 22.5 | -92 | |
| Oakland Raiders | 4-11 | L5 | 17.9 | 23.5 | -84 | |
| Tennessee Titans | 4-11 | L2 | 19.1 | 25.4 | -95 | |
| Green Bay Packers | 3-12 | L2 | 18.3 | 21.8 | -52 | |
| New York Jets | 3-12 | L2 | 14.0 | 21.9 | -119 | |
| New Orleans Saints | 3-12 | L4 | 14.8 | 24.7 | -149 | |
| San Francisco 49ers | 3-12 | W1 | 14.6 | 27.4 | -192 | |
| Houston Texans | 2-13 | L1 | 16.2 | 27.4 | -168 |
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