| 12 | Houston Astros |
| Postseason Teams | World Series Winner |
The 2022 World Series winner was the Houston Astros, who defeated the Philadelphia Phillies in 6 games. The final game was on on Nov 5, 2022, in which the Astros won 4-1 at home.
The 2022 World Series started on Oct 28, 2022 and ended on Nov 5, 2022, lasting 6 games.
The Los Angeles Dodgers had the best regular season record in the 2022 MLB season at 111-51.
The Los Angeles Dodgers had the best run differential in the 2022 regular season at +334 runs.
The Washington Nationals had the worst run differential in the 2022 regular season at -252 runs.
The Los Angeles Dodgers had the most runs per game in the 2022 regular season at 5.23 RPG.
The Los Angeles Dodgers allowed the fewest runs per game in the 2022 regular season at 3.17 runs allowed per game.
| Team | Record | Streak | RPG | RPG Allowed | Run Differential | Playoff Result |
|---|---|---|---|---|---|---|
| Los Angeles Dodgers | 111-51 | W1 | 5.23 | 3.17 | +334 | Lost NLDS |
| Houston Astros | 106-56 | W2 | 4.55 | 3.20 | +219 | Won WS |
| Atlanta Braves | 101-61 | L1 | 4.87 | 3.76 | +180 | Lost NLDS |
| New York Mets | 101-61 | W3 | 4.77 | 3.74 | +166 | Lost NLWC |
| New York Yankees | 99-63 | L2 | 4.98 | 3.50 | +240 | Lost ALCS |
| St. Louis Cardinals | 93-69 | L1 | 4.77 | 3.93 | +135 | Lost NLWC |
| Toronto Blue Jays | 92-70 | L1 | 4.78 | 4.19 | +96 | Lost ALWC |
| Cleveland Guardians | 92-70 | W2 | 4.31 | 3.91 | +64 | Lost ALDS |
| Seattle Mariners | 90-72 | W3 | 4.26 | 3.85 | +67 | Lost ALDS |
| San Diego Padres | 89-73 | L1 | 4.35 | 4.07 | +45 | Lost NLCS |
| Philadelphia Phillies | 87-75 | L2 | 4.61 | 4.23 | +62 | Lost WS |
| Tampa Bay Rays | 86-76 | L5 | 4.11 | 3.79 | +52 | Lost ALWC |
| Milwaukee Brewers | 86-76 | L1 | 4.48 | 4.25 | +37 | |
| Baltimore Orioles | 83-79 | W1 | 4.16 | 4.25 | -14 | |
| San Francisco Giants | 81-81 | W1 | 4.42 | 4.30 | +19 | |
| Chicago White Sox | 81-81 | L1 | 4.23 | 4.43 | -31 | |
| Minnesota Twins | 78-84 | W1 | 4.30 | 4.22 | +12 | |
| Boston Red Sox | 78-84 | W3 | 4.54 | 4.86 | -52 | |
| Arizona Diamondbacks | 74-88 | W1 | 4.33 | 4.57 | -38 | |
| Chicago Cubs | 74-88 | W1 | 4.06 | 4.51 | -74 | |
| Los Angeles Angels | 73-89 | L3 | 3.85 | 4.12 | -45 | |
| Miami Marlins | 69-93 | W1 | 3.62 | 4.17 | -90 | |
| Texas Rangers | 68-94 | W2 | 4.36 | 4.59 | -36 | |
| Colorado Rockies | 68-94 | L1 | 4.31 | 5.39 | -175 | |
| Detroit Tigers | 66-96 | L3 | 3.44 | 4.40 | -156 | |
| Kansas City Royals | 65-97 | L2 | 3.95 | 5.00 | -170 | |
| Cincinnati Reds | 62-100 | L1 | 4.00 | 5.03 | -167 | |
| Pittsburgh Pirates | 62-100 | W1 | 3.65 | 5.04 | -226 | |
| Oakland Athletics | 60-102 | W4 | 3.51 | 4.75 | -202 | |
| Washington Nationals | 55-107 | L5 | 3.72 | 5.28 | -252 |
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