Based on winning percentage, the 1906 Chicago Cubs had the best regular season in history at 116-36, but did not win the World Series. The Cubs lost to the Chicago White Sox in the World Series.
The 1906 Chicago Cubs and 2001 Seattle Mariners are tied for the most wins in a single MLB season with 116 wins.
There has never been a MLB team with an undefeated regular season. The closest anybody has come is the 2020 Los Angeles Dodgers, who had 17 losses, however that happened in a 60 game season.
There have been 7 teams in MLB history who have won at least 110 games. This most recently happened in 2022, when the Los Angeles Dodgers went 111-51.
There have been 31 teams in MLB history who have won at least 105 games. A 105-win season most recently happened in 2022 when 2 teams, the Houston Astros (106) and the Los Angeles Dodgers (111) both won at least 105 games.
There have been 116 teams in MLB history who have won at least 100 games. A 100-win season most recently happened in 2022 when 4 teams, the Atlanta Braves (101), the New York Mets (101), the Houston Astros (106) and the Los Angeles Dodgers (111) all won at least 100 games.
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