The Cleveland Spiders have the longest losing streak of regular season games in MLB history at 24 straight games. During this streak they lost to their opponents by an average of 5.9 runs. The streak occurred entirely during the 1899 season.
The Arizona Diamondbacks have the longest active losing streak of regular season games at 4 straight games. The streak started in the 2023 season with a loss to the Chicago White Sox on Sep 28, 2023. Their most recent loss was to the Houston Astros on Oct 1, 2023.
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